COVID Vax Poses Increased Risk of Blood Clot, Red Blood Cell Destruction in People with Blood Disorders: Frontiers

A new journal article published in Frontiers sheds light on the possible complications of COVID-19 vaccines for people with hematological disorders and hypercoagulability states.

A hematological disorder is a medical condition that affects the blood and blood-forming tissues, while hypercoagulability states are medical conditions characterized by an increased tendency of the blood to clot.

VACCINE RISKS FOR PEOPLE WITH BLOOD DISORDERS:

The article warns that individuals with conditions such as “glucose 6-phosphate dehydrogenase (G6PD) deficiency, thalassemia, sickle cell disease (SCD), pyruvate kinase enzyme deficiency (PKD), thrombophilia, hypereosinophilic syndromes, Glanzmann syndrome, sticky platelet syndrome, immune thrombocytopenia, and antithrombin deficiency” may be at “increased risk” of thrombosis and hemolysis following vaccination.

Thrombosis is the formation of a blood clot inside a blood vessel. Hemolysis is the breakdown of red blood cells.

The article also explains that COVID jabs can “trigger” endothelial damage, inflammation, platelet activation, cytokine storm, oxidative stress, and altered coagulation, all of which can contribute to thrombosis in patients.

Definitions for the above disorders are as follows:

  • Endothelial damage: Injury to the inner lining of blood vessels that can disrupt the normal balance of clotting and anti-clotting mechanisms.
  • Inflammation: A response of the body’s immune system that can promote clotting.
  • Platelet activation: The process by which platelets become sticky and clump together to form clots.
  • Cytokine storm: An excessive and uncontrolled immune response that can lead to inflammation and a pro-thrombotic state.
  • Oxidative stress: A condition characterized by an imbalance between harmful substances and the body’s ability to get rid of them, which can promote clot formation.
  • Altered coagulation: Changes in the normal balance between clotting and anti-clotting mechanisms that can lead to excessive clot formation.

VACCINES LINKED TO ADVERSE EFFECTS IN PEOPLE WITH BLOOD DISORDERS:

Thrombosis, portal vein thrombosis (PVT), immune thrombotic thrombocytopenia (ITT), deep vein thrombosis (DVT), vaccine-induced immune thrombocytopenia (VITT), and heparin-induced thrombocytopenia (HIT) are also “reported as vaccine-induced adverse effects in people with blood disorders,” the Turkish authors confirm.

Definitions for these disorders are as follows:

  • Portal vein thrombosis (PVT): A blood clot that forms in the vein that carries blood from the intestines to the liver.
  • Immune thrombotic thrombocytopenia (ITT): A rare disorder that causes blood clots and low platelet count.
  • Deep vein thrombosis (DVT): A blood clot that forms in a vein deep inside the body, usually in the legs.
  • Vaccine-induced immune thrombocytopenia (VITT): A rare condition where blood clots form in the body and cause low platelet count after receiving certain vaccines, such as the AstraZeneca COVID-19 vaccine.
  • Heparin-induced thrombocytopenia (HIT): A reaction to heparin, a blood-thinning medication, where the immune system attacks platelets, leading to blood clot formation.

CALLS FOR EXTRA CAUTION, SUPPORTIVE CARE, & FUTURE RESEARCH:

The publication authors call for “extra caution and supportive care” for patients with hematological disorders following vaccination.

The authors of the article stress that further studies are needed to fully understand the mechanisms behind COVID-19 vaccine-induced thrombosis in patients with hematological disorders “to prevent vaccine-related complications.”

Read the full publication here:

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