President Donald Trump has announced a new milestone in lowering prescription drug prices for Americans, securing “Most Favored Nation” (MFN) agreements with nine additional pharmaceutical companies — a move praised by Dr. Mehmet Oz as the culmination of hardball negotiations to end inflated U.S. drug prices.
Speaking on The Alex Marlow Show Friday, Oz revealed the bold directive Trump gave him during their work together on health policy: “Go look these pharma executives in the face” and challenge the logic of charging Americans up to three times what other nations pay for the same drugs. “And guess what?” Oz said. “He was right. They’ve all sort of come back and said, ‘You caught us.’”
The new MFN deals bring Trump’s total to 14 since late September. Under these agreements, drug prices paid by State Medicaid programs will now match the lowest available prices globally, potentially saving American taxpayers billions. Any new medications these companies produce must also be sold at MFN pricing. In addition, a new Trump-backed website, TrumpRx, will begin offering steep discounts to the public starting in January.
At a press conference alongside Oz, Health and Human Services Secretary Robert F. Kennedy Jr., and several pharmaceutical leaders, Trump called the deals “the greatest victory for patient affordability in American history.”
“What we’re doing is saying — whatever the lowest price is in the world, we’re going to get it. Not ten times more, not three times more. The same price,” Trump declared. “We’ve been laughed at and scoffed at for years — no more.”
Oz contrasted Trump’s results with the Democrats’ Affordable Care Act, saying, “They throw more money at the problem and hope it goes away. This is real change.”
The MFN strategy, pioneered during Trump’s first term, now appears to be central to his 2025 health care push — an approach that Oz said could transform affordability and make prescription drugs genuinely accessible.

